Nasonex nasal steroid

The majority of side effects from topical steroids occur within the nose at the site of local application. These side effects commonly include nasal irritation and nose bleeds . Should these symptoms occur, a person should stop using the nasal steroid for a few days, and then re-start the medication using the appropriate technique . If bleeding and irritation continue to occur, the nasal steroid should not be used any longer. A person who continues to use a nasal steroid despite these local side effects is at risk for septal perforation .

A total of 1008 patients aged 12 years and older received NASONEX Nasal Spray 50 mcg 200 mcg/day (n=506) or placebo (n=502) for 15 days. Adverse events that occurred more frequently in patients treated with NASONEX Nasal Spray 50 mcg than in patients with the placebo included sinus headache (% in NASONEX Nasal Spray 50 mcg group vs. % in placebo) and epistaxis (1% in NASONEX Nasal Spray 50 mcg group vs. % in placebo) and the overall adverse event profile was similar to that observed in the other allergic rhinitis trials.

Mometasone furoate increased chromosomal aberrations in an in vitro Chinese hamster ovary-cell assay, but did not increase chromosomal aberrations in an in vitro Chinese hamster lung cell assay. Mometasone furoate was not mutagenic in the Ames test or mouse- lymphoma assay, and was not clastogenic in an in vivo mouse micronucleus assay and a rat bone marrow chromosomal aberration assay or a mouse male germ -cell chromosomal aberration assay. Mometasone furoate also did not induce unscheduled DNA synthesis in vivo in rat hepatocytes.

Nasonex nasal steroid

nasonex nasal steroid

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