Ephedrine medication should be taken as advised by your doctor. Always refer to the instructions leaflet for the accurate dosage. It is not necessary to take ephedrine with food. In case there is some kind of stomach irritation, chose to take the drug with food. If you are a regular user of ephedrine and happen to miss a dose, you are advised to take it as soon as possible. If your next dose is just around the corner, forget the missed dose and get back on the regular dosage routine. It is highly unadvisable to take two doses at a time.